Bilinear programming
The well-known bottleneck of systems pharmacology, i. e., systems biology applied to pharmacology, refers to the model parameters determination from experimentally measured datasets. This paper represents the development of our earlier studies devoted to inverse (ill-posed) problems of model parameters identification. The key feature of this research is the introduction of control (or periodic forcing by an input signal being a drug intake) of the nonlinear model of drug-induced enzyme production...
We consider point sets in (Z^2,n) where no three points are on a line – also called caps or arcs. For the determination of caps with maximum cardinality and complete caps with minimum cardinality we provide integer linear programming formulations and identify some values for small n.
Las propiedades geométricas del conjunto factible del dual de un problema semiinfinito lineal son análogas a las correspondientes para el caso finito. En este trabajo mostramos cómo, a partir de la caracterización algebraica de vértices y direcciones extremas, se consigue la correspondiente para aristas infinitas, estableciéndose así las bases para una extensión del método simplex a programas semiinfinitos lineales.
European directives and related national technical standards force the substantial reduction of energy consumption of all types of buildings. This can be done thanks to the massive insulation and the improvement of quality of building enclosures, using the simple evaluation assuming the one-dimensional stationary heat conduction. However, recent applications of advanced materials, structures and technologies force the proper physical, mathematical and computational analysis coming from the thermodynamic...