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In this article, we build a mathematical model to understand the
formation of a tree leaf. Our model is based on the idea that a leaf
tends to maximize internal efficiency by developing an efficient
transport system for transporting water and nutrients. The meaning
of “the efficient transport system” may vary as the type of the
tree leave varies. In this article, we will demonstrate that tree
leaves have different shapes and venation patterns mainly because
they have adopted different efficient...
We discuss theoretical and experimental approaches to three distinct
developmental systems that illustrate how theory can influence experimental work
and vice-versa. The chosen systems – Drosophila melanogaster,
bacterial pattern formation, and pigmentation patterns – illustrate the
fundamental physical processes of signaling, growth and cell division, and cell
movement involved in pattern formation and development. These systems exemplify
the current state of theoretical and experimental understanding...
Collective cell motility and its guidance via cell-cell contacts is instrumental in several morphogenetic and pathological processes such as vasculogenesis or tumor growth. Multicellular sprout elongation, one of the simplest cases of collective motility, depends on a continuous supply of cells streaming along the sprout towards its tip. The phenomenon is often explained as leader cells pulling the rest of the sprout forward via cell-cell adhesion. Building on an empirically demonstrated analogy...
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