Genetic linkage analysis: An irregular statistical problem.
In this paper several models in virus dynamics with and without immune response are discussed concerning asymptotic behaviour. The case of immobile cells but diffusing viruses and T-cells is included. It is shown that, depending on the value of the basic reproductive number R0 of the virus, the corresponding equilibrium is globally asymptotically stable. If R0 < 1 then the virus-free equilibrium has this property, and in case R0 > 1 there is a unique disease equilibrium which takes over this...
The authors consider the nonlinear difference equation with . They give sufficient conditions for the unique positive equilibrium of (0.1) to be a global attractor of all positive solutions. The results here are somewhat easier to apply than those of other authors. An application to a model of blood cell production is given.
We describe the global dynamics of a disease transmission model between two regions which are connected via bidirectional or unidirectional transportation, where infection occurs during the travel as well as within the regions. We define the regional reproduction numbers and the basic reproduction number by constructing a next generation matrix. If the two regions are connected via bidirectional transportation, the basic reproduction number characterizes the existence of equilibria as well as...
A model of chemotaxis is analyzed that prevents blow-up of solutions. The model consists of a system of nonlinear partial differential equations for the spatial population density of a species and the spatial concentration of a chemoattractant in n-dimensional space. We prove the existence of solutions, which exist globally, and are L∞-bounded on finite time intervals. The hypotheses require nonlocal conditions on the species-induced production of the chemoattractant.