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Stability Analysis of Cell Dynamics in Leukemia

H. Özbay, C. Bonnet, H. Benjelloun, J. Clairambault (2012)

Mathematical Modelling of Natural Phenomena

In order to better understand the dynamics of acute leukemia, and in particular to find theoretical conditions for the efficient delivery of drugs in acute myeloblastic leukemia, we investigate stability of a system modeling its cell dynamics. The overall system is a cascade connection of sub-systems consisting of distributed delays and static nonlinear feedbacks. Earlier results on local asymptotic stability are improved by the analysis of the linearized...

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