Displaying 61 – 80 of 89

Showing per page

Contributi delle Scienze Matematiche ed Informatiche al sequenziamento genomico su larga scala

Raffaele Giancarlo, Sabrina Mantaci (2001)

Bollettino dell'Unione Matematica Italiana

Nel panorama della scienza contemporanea, la biologia molecolare ha recentemente assunto un ruolo di fondamentale importanza. Il bisognocrescente di conoscere intere sequenze genomiche e l’esigenza, ancora piùpressante, di analizzare e confrontare tali sequenze per poter dedurre funzionalità e discendenze comuni, ha reso necessaria l’integrazione delleusuali tecniche sperimentali, proprie della ricerca biologica, con le metodologie formali della matematica e dell’informatica. Queste motivazioni...

Convergence analysis for principal component flows

Shintaro Yoshizawa, Uwe Helmke, Konstantin Starkov (2001)

International Journal of Applied Mathematics and Computer Science

A common framework for analyzing the global convergence of several flows for principal component analysis is developed. It is shown that flows proposed by Brockett, Oja, Xu and others are all gradient flows and the global convergence of these flows to single equilibrium points is established. The signature of the Hessian at each critical point is determined.

Could changes in national tuberculosis vaccination policies be ill-informed ?

D.J. Gerberry, F.A. Milner (2012)

Mathematical Modelling of Natural Phenomena

National policies regarding the BCG vaccine for tuberculosis vary greatly throughout the international community and several countries are currently considering discontinuing universal vaccination. Detractors of BCG point to its uncertain effectiveness and its interference with the detection and treatment of latent tuberculosis infection (LTBI). In order to quantify the trade-off between vaccination and treatment of LTBI, a mathematical model was designed and calibrated to data from Brazil, Ghana,...

Counting number of cells and cell segmentation using advection-diffusion equations

Peter Frolkovič, Karol Mikula, Nadine Peyriéras, Alex Sarti (2007)

Kybernetika

We develop a method for counting number of cells and extraction of approximate cell centers in 2D and 3D images of early stages of the zebra-fish embryogenesis. The approximate cell centers give us the starting points for the subjective surface based cell segmentation. We move in the inner normal direction all level sets of nuclei and membranes images by a constant speed with slight regularization of this flow by the (mean) curvature. Such multi- scale evolutionary process is represented by a geometrical...

Coupled analytical and numerical approach to uncovering new regulatory mechanisms of intracellular processes

Jarosław Śmieja (2010)

International Journal of Applied Mathematics and Computer Science

The paper deals with the analysis of signaling pathways aimed at uncovering new regulatory processes regulating cell responses. First, general issues of comparing simulation and experimental data are discussed, and various aspects of data normalization are covered. Then, a model of a particular signaling pathway, induced by Interferon-β, is briefly introduced. It serves as an example illustrating how mathematical modeling can be used for inferring the structure of a regulatory system governing the...

Coupling a branching process to an infinite dimensional epidemic process***

Andrew D. Barbour (2010)

ESAIM: Probability and Statistics

Branching process approximation to the initial stages of an epidemic process has been used since the 1950's as a technique for providing stochastic counterparts to deterministic epidemic threshold theorems. One way of describing the approximation is to construct both branching and epidemic processes on the same probability space, in such a way that their paths coincide for as long as possible. In this paper, it is shown, in the context of a Markovian model of parasitic infection, that coincidence...

Coupling of chemical reaction with flow and molecular transport

Ulrich Maas (1995)

Applications of Mathematics

During the last years the interest in the numerical simulation of reacting flows has grown considerably. Numerical methods are available, which allow to couple chemical kinetics with flow and molecular transport. However, the use of detailed physical and chemical models, involving more than 100 chemical species, and thus more than 100 species conservation equations, is restricted to very simple flow configurations like one-dimensional systems or two-dimensional systems with very simple geometries,...

Currently displaying 61 – 80 of 89