Simpel modelling of extracellular matrix alignment in dermal wound healing. I: Cell flux induced alignment.
Solutions for the cell cycle in cell lines derived from human tumors.
Solutions of inverse problems with potential application for breast tumour detection using microwave measurements.
Solving algebraic problems in propositional logic by tableau.
Spatial correlation of gene expression measures in tissue microarry core analysis.
Spatial Dynamics of Contact-Activated Fibrin Clot Formation in vitro and in silico in Haemophilia B: Effects of Severity and Ahemphil B Treatment
Spatial dynamics of fibrin clot formation in non-stirred system activated by glass surface was studied as a function of FIX activity. Haemophilia B plasma was obtained from untreated patients with different levels of FIX deficiency and from severe haemophilia B patient treated with FIX concentrate (Ahemphil B) during its clearance with half-life t1/2=12 hours. As reported previously (Ataullakhanov et al. Biochim Biophys Acta 1998; 1425: 453-468), clot growth in space showed two distinct phases:...
Spatial evolutionary games of interaction among generic cancer cells.
Spatial tumor-immune modeling.
Spatio-Temporal Modelling of the p53–mdm2 Oscillatory System
In this paper we investigate the role of spatial effects in determining the dynamics of a subclass of signalling pathways characterised by their ability to demonstrate oscillatory behaviour. To this end, we formulate a simple spatial model of the p53 network that accounts for both a negative feedback and a transcriptional delay. We show that the formation of protein density patterns can depend on the shape of the cell, position of the nucleus, and the protein diffusion rates. The temporal...
Stability analysis of a model of atherogenesis: an energy estimate approach. II.
Stability analysis of a model of atherogenesis: an energy estimate approach.
Stability Analysis of Cell Dynamics in Leukemia
In order to better understand the dynamics of acute leukemia, and in particular to find theoretical conditions for the efficient delivery of drugs in acute myeloblastic leukemia, we investigate stability of a system modeling its cell dynamics. The overall system is a cascade connection of sub-systems consisting of distributed delays and static nonlinear feedbacks. Earlier results on local asymptotic stability are improved by the analysis of the linearized...
Stability of a two-strain tuberculosis model with general contact rate.
Stability results for a class of differential equation and application in medicine.
Statistical analysis of diabetes mellitus
This paper deals with an application of regression analysis to the regulation of the blood-sugar under diabetes mellitus. Section 2 gives a description of Gram-Schmidt orthogonalization, while Section 3 discusses the difference between Gauss-Markov estimation and Least Squares Estimation. Section 4 is devoted to the statistical analysis of the blood-sugar during the night. The response change of blood-sugar is explained by three variables: time, food and physical activity ("Bewegung"). At the beginning...
Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines.
The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.
Stochastic approach to the process of red cell destruction
Stochastic models of progression of cancer andtheir use in controlling cancer-related mortality
A construction of a realistic statistical model of lung cancer risk and progression is proposed. The essential elements of the model are genetic and behavioral determinants of susceptibility, progression of the disease from precursor lesions through early (localized) tumors to disseminated disease, detection by various modalities, and medical intervention. Using model estimates as a foundation, mortality reduction caused by early-detection and intervention programs can be predicted under different...
SV40 assembly in vivo and in vitro.
: a proposed framework for using topic maps to manage information in blood donation units.