We analyse the influence of diffusion and space distribution of cells in a simple model of interactions between an activated immune system and malignant gliomas, among which the most aggressive one is GBM Glioblastoma Multiforme. It turns out that diffusion cannot affect stability of spatially homogeneous steady states. This suggests that there are two possible outcomes-the solution is either attracted by the positive steady state or by the semitrivial one. The semitrivial steady state describes...

We consider a reaction-diffusion system of activator-inhibitor type which is subject to Turing's diffusion-driven instability. It is shown that unilateral obstacles of various type for the inhibitor, modeled by variational inequalities, lead to instability of the trivial solution in a parameter domain where it would be stable otherwise. The result is based on a previous joint work with I.-S. Kim, but a refinement of the underlying theoretical tool is developed. Moreover, a different regime of parameters...