We use the concept of intrinsic metrics to give a new definition for an isoperimetric constant of a graph. We use this novel isoperimetric constant to prove a Cheeger-type estimate for the bottom of the spectrum which is nontrivial even if the vertex degrees are unbounded.

We investigate the criticality of the one term $2n$-order difference operators $l{\left(y\right)}_k={\Delta }^n\left(r_k{\Delta }^n{y}_k\right)$. We explicitly determine the recessive and the dominant system of solutions of the equation $l{\left(y\right)}_k=0$. Using their structure we prove a criticality criterion.