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Data mining methods for gene selection on the basis of gene expression arrays

Michał Muszyński, Stanisław Osowski (2014)

International Journal of Applied Mathematics and Computer Science

The paper presents data mining methods applied to gene selection for recognition of a particular type of prostate cancer on the basis of gene expression arrays. Several chosen methods of gene selection, including the Fisher method, correlation of gene with a class, application of the support vector machine and statistical hypotheses, are compared on the basis of clustering measures. The results of applying these individual selection methods are combined together to identify the most often selected...

Decay and asymptotic behavior of solutions of the Keller-Segel system of degenerate and nondegenerate type

Takayoshi Ogawa (2006)

Banach Center Publications

We classify the global behavior of weak solutions of the Keller-Segel system of degenerate and nondegenerate type. For the stronger degeneracy, the weak solution exists globally in time and has a uniform time decay under some extra conditions. If the degeneracy is weaker, the solution exhibits a finite time blow up if the data is nonnegative. The situation is very similar to the semilinear case. Some additional discussion is also presented.

Delay Model of Hematopoietic Stem Cell Dynamics: Asymptotic Stability and Stability Switch

F. Crauste (2009)

Mathematical Modelling of Natural Phenomena

A nonlinear system of two delay differential equations is proposed to model hematopoietic stem cell dynamics. Each equation describes the evolution of a sub-population, either proliferating or nonproliferating. The nonlinearity accounting for introduction of nonproliferating cells in the proliferating phase is assumed to depend upon the total number of cells. Existence and stability of steady states are investigated. A Lyapunov functional is built to obtain the global asymptotic stability of the...

Delays induced in population dynamics

Eva Sánchez (2003)

Banach Center Publications

This paper provides an introduction to delay differential equations together with a short survey on state-dependent delay differential equations arising in population dynamics. Our main goal is to examine how the delays emerge from inner mechanisms in the model, how they induce oscillations and stability switches in the system and how the qualitative behaviour of a biological model depends on the form of the delay.

Design of a multivariable neural controller for control of a nonlinear MIMO plant

Stanisław Bańka, Paweł Dworak, Krzysztof Jaroszewski (2014)

International Journal of Applied Mathematics and Computer Science

The paper presents the training problem of a set of neural nets to obtain a (gain-scheduling, adaptive) multivariable neural controller for control of a nonlinear MIMO dynamic process represented by a mathematical model of Low-Frequency (LF) motions of a drillship over the drilling point at the sea bottom. The designed neural controller contains a set of neural nets that determine values of its parameters chosen on the basis of two measured auxiliary signals. These are the ship's current forward...

Deterministic and stochastic simulations of simple genetic circuits

Ofer Biham, Nathalie Q. Balaban, Adiel Loinger, Azi Lipshtat, Hagai B. Perets (2008)

Banach Center Publications

We analyze three simple genetic circuits which involve transcriptional regulation and feedback: the autorepressor, the switch and the repressilator, that consist of one, two and three genes, respectively. Such systems are commonly simulated using rate equations, that account for the concentrations of the mRNAs and proteins produced by these genes. Rate equations are suitable when the concentrations of the relevant molecules in a cell are large and fluctuations are negligible. However, when some...

Deterministic Chaos vs. Stochastic Fluctuation in an Eco-epidemic Model

P.S. Mandal, M. Banerjee (2012)

Mathematical Modelling of Natural Phenomena

An eco-epidemiological model of susceptible Tilapia fish, infected Tilapia fish and Pelicans is investigated by several author based upon the work initiated by Chattopadhyay and Bairagi (Ecol. Model., 136, 103–112, 2001). In this paper, we investigate the dynamics of the same model by considering different parameters involved with the model as bifurcation parameters in details. Considering the intrinsic growth rate of susceptible Tilapia fish as bifurcation parameter, we demonstrate the period doubling...

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