Hace apenas seis años, aparecieron dos números de la revista Estadística Española dedicados a la docencia de la estadística. Releyendo el artículo del profesor C. M. Cuadras y los amplios comentarios de un buen número de profesores del área sobre la docencia de la bioestadística en España, he tenido la impresión de que, a pesar de mantener su validez en líneas generales, la perspectiva ha cambiado radicalmente. En el cambio han intervenido, a mi parecer, dos hechos fundamentales: la irrupción de...

Si descrivono le attività e le responsabilità dello statistico professionale nella conduzione di una prova clinica in una industria farmaceutica o in un ente di ricerca.

In this work, a combined form of the Laplace transform method and the Adomian decomposition method is implemented to give an approximate solution of nonlinear systems of differential equations such as fish farm model with three components nutrient, fish and mussel. The technique is described and illustrated with a numerical example.

To establish lists of words with unexpected frequencies in long sequences, for instance in a molecular biology context, one needs to quantify the exceptionality of families of word frequencies in random sequences. To this aim, we study large deviation probabilities of multidimensional word counts for Markov and hidden Markov models. More specifically, we compute local Edgeworth expansions of arbitrary degrees for multivariate partial sums of lattice valued functionals of finite Markov...


We study a continuous-time discrete population structured by a vector of ages. Individuals reproduce asexually, age and die. The death rate takes interactions into account. Adapting the approach of Fournier and Méléard, we show that in a large population limit, the microscopic process converges to the measure-valued solution of an equation that generalizes the McKendrick-Von Foerster and Gurtin-McCamy PDEs in demography. The large deviations associated with this convergence are studied. The upper-bound...

We consider the spatial $𝛬$-Fleming–Viot process model (Electron. J. Probab.15(2010) 162–216) for frequencies of genetic types in a population living in ${ℝ}^d$, in the special case in which there are just two types of individuals, labelled $0$ and $1$. At time zero, everyone in a given half-space has type 1, whereas everyone in the complementary half-space has type $0$. We are concerned with patterns of frequencies of the two types at large space and time scales. We consider two cases, one in which the dynamics...

Two asexual density-dependent population dynamics models with age-dependence and child care are presented. One of them includes the random diffusion while in the other the population is assumed to be non-dispersing. The population consists of the young (under maternal care), juvenile, and adult classes. Death moduli of the juvenile and adult classes in both models are decomposed into the sum of two terms. The first presents death rate by the natural causes while the other describes the environmental...

This paper deals with a quasilinear parabolic-parabolic-elliptic attraction-repulsion chemotaxis system. Boundedness, stabilization and blow-up in this system of the fully parabolic and parabolic-elliptic-elliptic versions have already been proved. The purpose of this paper is to derive boundedness and stabilization in the parabolic-parabolic-elliptic version.

We consider the following reaction-diffusion equation:$$\left(\mathrm{KS}\right)\left\{\begin{array}{cccc}{u}_t=\nabla ·\left(\nabla u^m-u^{q-1}\nabla v\right),\hfill & x\in {ℝ}^N,0<t<\infty ,0=\Delta v-v+u,\hfill & x\in {ℝ}^N,0<t<\infty ,u(x,0)=u_0\left(x\right),\hfill & x\in {ℝ}^N,\hfill \end{array}\right.$$ where $N\ge 1,m>1,q\ge max\{m+\frac{2}{N},2\}$.
In [Sugiyama, Nonlinear Anal.63 (2005) 1051–1062; Submitted; J. Differential Equations (in press)] it was shown that in the case of $q\ge max\{m+\frac{2}{N},2\}$, the above problem (KS) is solvable globally in time for “small $L^{\frac{N(q-m)}{2}}$ data”. Moreover, the decay of the solution (u,v) in $L^p\left({ℝ}^N\right)$ was proved. In this paper, we consider the case of “$q\ge max\{m+\frac{2}{N},2\}$ and small $L^{\ell }$ data” with any fixed $\ell \ge \frac{N(q-m)}{2}$ and show that (i) there exists a time global solution (u,v) of (KS) and it decays to...

It is well established that resource variability generated by spatial patchiness and turbulence is an important influence on the growth and recruitment of planktonic fish larvae. Empirical data show fractal-like prey distributions, and simulations indicate that scale-invariant foraging strategies may be optimal. Here we show how larval growth and recruitment in a turbulent environment can be formulated as a hitting time problem for a jump-diffusion process. We present two theoretical results. Firstly,...