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Modelling Tuberculosis and Hepatitis B Co-infections

S. Bowong, J. Kurths (2010)

Mathematical Modelling of Natural Phenomena

Tuberculosis (TB) is the leading cause of death among individuals infected with the hepatitis B virus (HBV). The study of the joint dynamics of HBV and TB present formidable mathematical challenges due to the fact that the models of transmission are quite distinct. We formulate and analyze a deterministic mathematical model which incorporates of the co-dynamics of hepatitis B and tuberculosis. Two sub-models, namely: HBV-only and TB-only sub-models...

Monte Carlo simulation and analytic approximation of epidemic processes on large networks

Noémi Nagy, Péter Simon (2013)

Open Mathematics

Low dimensional ODE approximations that capture the main characteristics of SIS-type epidemic propagation along a cycle graph are derived. Three different methods are shown that can accurately predict the expected number of infected nodes in the graph. The first method is based on the derivation of a master equation for the number of infected nodes. This uses the average number of SI edges for a given number of the infected nodes. The second approach is based on the observation that the epidemic...

Numerical optimization of parameters in systems of differential equations

Martínek, Josef, Kučera, Václav (2023)

Programs and Algorithms of Numerical Mathematics

We present results on the estimation of unknown parameters in systems of ordinary differential equations in order to fit the output of models to real data. The numerical method is based on the nonlinear least squares problem along with the solution of sensitivity equations corresponding to the differential equations. We will present the performance of the method on the problem of fitting the output of basic compartmental epidemic models to data from the Covid-19 epidemic. This allows us to draw...

On a stochastic SIR model

Elisabetta Tornatore, Stefania Maria Buccellato (2007)

Applicationes Mathematicae

We consider a stochastic SIR system and we prove the existence, uniqueness and positivity of solution. Moreover the existence of an invariant measure under a suitable condition on the coefficients is studied.

On the Dynamics of a Two-Strain Influenza Model with Isolation

F. Chamchod, N.F. Britton (2012)

Mathematical Modelling of Natural Phenomena

Influenza has been responsible for human suffering and economic burden worldwide. Isolation is one of the most effective means to control the disease spread. In this work, we incorporate isolation into a two-strain model of influenza. We find that whether strains of influenza die out or coexist, or only one of them persists, it depends on the basic reproductive number of each influenza strain, cross-immunity between strains, and isolation rate. We propose criteria that may be useful for controlling...

On the dynamics of a vaccination model with multiple transmission ways

Shu Liao, Weiming Yang (2013)

International Journal of Applied Mathematics and Computer Science

In this paper, we present a vaccination model with multiple transmission ways and derive the control reproduction number. The stability analysis of both the disease-free and endemic equilibria is carried out, and bifurcation theory is applied to explore a variety of dynamics of this model. In addition, we present numerical simulations to verify the model predictions. Mathematical results suggest that vaccination is helpful for disease control by decreasing the control reproduction number below unity....

On the global dynamics of the cancer AIDS-related mathematical model

Konstantin E. Starkov, Corina Plata-Ante (2014)

Kybernetika

In this paper we examine some features of the global dynamics of the four-dimensional system created by Lou, Ruggeri and Ma in 2007 which describes the behavior of the AIDS-related cancer dynamic model in vivo. We give upper and lower ultimate bounds for concentrations of cell populations and the free HIV-1 involved in this model. We show for this dynamics that there is a positively invariant polytope and we find a few surfaces containing omega-limit sets for positive half trajectories in the positive...

Optimal Screening in Structured SIR Epidemics

B. Ainseba, M. Iannelli (2012)

Mathematical Modelling of Natural Phenomena

We present a model for describing the spread of an infectious disease with public screening measures to control the spread. We want to address the problem of determining an optimal screening strategy for a disease characterized by appreciable duration of the infectiveness period and by variability of the transmission risk. The specific disease we have in mind is the HIV infection. However the model will apply to a disease for which class-age structure...

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