In this paper, we study the question of existence and uniqueness of entropy solutions for a system of nonlinear partial differential equations with general anisotropic diffusivity and transport effects, supplemented with no-flux boundary conditions, modeling the spread of an epidemic disease through a heterogeneous habitat.
We give a survey of results on global stability for deterministic compartmental epidemiological models. Using Lyapunov techniques we revisit a classical result, and give a simple proof. By the same methods we also give a new result on differential susceptibility and infectivity models with mass action and an arbitrary number of compartments. These models encompass the so-called differential infectivity and staged progression models. In the two cases we prove that if the basic reproduction ratio...
We present a unified mathematical approach to epidemiological models with parametric heterogeneity, i.e., to the models that describe individuals in the population as having specific parameter (trait) values that vary from one individuals to another. This is a natural framework to model, e.g., heterogeneity in susceptibility or infectivity of individuals. We review, along with the necessary theory, the results obtained using the discussed approach....
An SEIR model with periodic coefficients in epidemiology is considered. The global existence of periodic solutions with strictly positive components for this model is established by using the method of coincidence degree. Furthermore, a sufficient condition for the global stability of this model is obtained. An example based on the transmission of respiratory syncytial virus (RSV) is included.