We introduce the notion of an instanton bundle on a Fano threefold of index 2. For such bundles we give an analogue of a monadic description and discuss the curve of jumping lines. The cases of threefolds of degree 5 and 4 are considered in a greater detail.
We study a class of torsion-free sheaves on complex projective spaces which generalize the much studied mathematical instanton bundles. Instanton sheaves can be obtained as cohomologies of linear monads and are shown to be semistable if its rank is not too large, while semistable torsion-free sheaves satisfying certain cohomological conditions are instanton. We also study a few examples of moduli spaces of instanton sheaves.