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Quantitative Analysis of Melanocyte Migration in vitro Based on Automated Cell Tracking under Phase Contrast Microscopy Considering the Combined Influence of Cell Division and Cell-Matrix Interactions

V. Letort, S. Fouliard, G. Letort, I. Adanja, M. Kumasaka, S. Gallagher, O. Debeir, L. Larue, F. Xavier (2010)

Mathematical Modelling of Natural Phenomena

The aim of this study was to describe and analyze the regulation and spatio-temporal dynamics of melanocyte migration in vitro and its coupling to cell division and interaction with the matrix. The melanocyte lineage is particularly interesting because it is involved in both embryonic development and oncogenesis/metastasis (melanoma). Biological experiments were performed on two melanocyte cell lines established from wild-type and β-catenin-transgenic...

Random coefficients bifurcating autoregressive processes

Benoîte de Saporta, Anne Gégout-Petit, Laurence Marsalle (2014)

ESAIM: Probability and Statistics

This paper presents a new model of asymmetric bifurcating autoregressive process with random coefficients. We couple this model with a Galton−Watson tree to take into account possibly missing observations. We propose least-squares estimators for the various parameters of the model and prove their consistency, with a convergence rate, and asymptotic normality. We use both the bifurcating Markov chain and martingale approaches and derive new results in both these frameworks.

Random real trees

Jean-François Le Gall (2006)

Annales de la faculté des sciences de Toulouse Mathématiques

We survey recent developments about random real trees, whose prototype is the Continuum Random Tree (CRT) introduced by Aldous in 1991. We briefly explain the formalism of real trees, which yields a neat presentation of the theory and in particular of the relations between discrete Galton-Watson trees and continuous random trees. We then discuss the particular class of self-similar random real trees called stable trees, which generalize the CRT. We review several important results concerning stable...

Rapid Emergence of Co-colonization with Community-acquired and Hospital-Acquired Methicillin-Resistant Staphylococcus aureus Strains in the Hospital Setting

E. M. C. D’Agata, G. F. Webb, J. Pressley (2010)

Mathematical Modelling of Natural Phenomena

Background: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), a novel strain of MRSA, has recently emerged and rapidly spread in the community. Invasion into the hospital setting with replacement of the hospital-acquired MRSA (HA-MRSA) has also been documented. Co-colonization with both CA-MRSA and HA-MRSA would have important clinical implications given differences in antimicrobial susceptibility profiles and the potential...

Rational Constants of Generic LV Derivations and of Monomial Derivations

Janusz Zieliński (2013)

Bulletin of the Polish Academy of Sciences. Mathematics

We describe the fields of rational constants of generic four-variable Lotka-Volterra derivations. Thus, we determine all rational first integrals of the corresponding systems of differential equations. Such systems play a role in population biology, laser physics and plasma physics. They are also an important part of derivation theory, since they are factorizable derivations. Moreover, we determine the fields of rational constants of a class of monomial derivations.

Reaction-Diffusion Modelling of Interferon Distribution in Secondary Lymphoid Organs

G. Bocharov, A. Danilov, Yu. Vassilevski, G.I. Marchuk, V.A. Chereshnev, B. Ludewig (2011)

Mathematical Modelling of Natural Phenomena

This paper proposes a quantitative model of the reaction-diffusion type to examine the distribution of interferon-α (IFNα) in a lymph node (LN). The numerical treatment of the model is based on using an original unstructured mesh generation software Ani3D and nonlinear finite volume method for diffusion equations. The study results in suggestion that due to the variations in hydraulic conductivity of various zones of the secondary lymphoid organs...

Reaction-Difusion Model of Early Carcinogenesis: The Effects of Influx of Mutated Cells

Anna Marciniak-Czochra, Marek Kimmel (2008)

Mathematical Modelling of Natural Phenomena

In this paper we explore a new model of field carcinogenesis, inspired by lung cancer precursor lesions, which includes dynamics of a spatially distributed population of pre-cancerous cells c(t, x), constantly supplied by an influx μ of mutated normal cells. Cell proliferation is controlled by growth factor molecules bound to cells, b(t, x). Free growth factor molecules g(t, x) are produced by precancerous cells and may diffuse before they become bound to other cells. The purpose of modelling is...

Recognition of atherosclerotic plaques and their extended dimensioning with computerized tomography angiography imaging

Tomasz Markiewicz, Mirosław Dziekiewicz, Marek Maruszyński, Romana Bogusławska-Walecka, Wojciech Kozłowski (2014)

International Journal of Applied Mathematics and Computer Science

In this paper the authors raise the issue of automatic discrimination of atherosclerotic plaques within an artery lumen based on numerical and statistical thresholding of Computerized Tomography Angiographic (CTA) images and their advanced dimensioning as a support for preoperative vessel assessment. For the study, a set of tomograms of the aorta, as well as the ilio-femoral and femoral arteries were examined. In each case a sequence of about 130-480 images of the artery cutoff planes were analyzed...

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