In this paper, we consider solutions to the following chemotaxis system with general sensitivity $$\left\{\begin{array}{c}\tau u_t=\Delta u-\nabla ·\left(u\nabla \chi \left(v\right)\right)\text{in}\Omega \times (0,\infty ),\hfill \\ \eta v_t=\Delta v-v+u\text{in}\Omega \times (0,\infty ),\hfill \\ {\displaystyle \frac{\partial u}{\partial \nu }=\frac{\partial u}{\partial \nu }=0\text{on}\partial \Omega \times (0,\infty ).}\hfill \end{array}\right.$$ Here, $\tau$ and $\eta$ are positive constants, $\chi$ is a smooth function on $(0,\infty )$ satisfying ${\chi }^{\text{'}}(·)>0$ and $\Omega$ is a bounded domain of ${𝐑}^n$ ($n\ge 2$). It is well known that the chemotaxis system with direct sensitivity ($\chi \left(v\right)={\chi }_{0}v$, ${\chi }_0>0$) has blowup solutions in the case where $n\ge 2$. On the other hand, in the case where $\chi \left(v\right)={\chi }_{0}logv$ with $0<{\chi }_0\ll 1$, any solution to the system exists globally in time and is bounded. We present a sufficient condition for the boundedness of...

This paper extends the volume filling chemotaxis model [18, 26] by taking into account the cell population interactions. The extended chemotaxis models have nonlinear diffusion and chemotactic sensitivity depending on cell population density, which is a modification of the classical Keller-Segel model in which the diffusion and chemotactic sensitivity are constants (linear). The existence and boundedness of global solutions of these models are discussed and...

This paper contains some results concerning self-similar radial solutions for some system of chemotaxis. This kind of solutions describe asymptotic profiles of arbitrary solutions with small mass. Our approach is based on a fixed point analysis for an appropriate integral operator acting on a suitably defined convex subset of some cone in the space of bounded and continuous functions.

We develop the analogy between self-gravitating Brownian particles and bacterial populations. In the high friction limit, the self-gravitating Brownian gas is described by the Smoluchowski-Poisson system. These equations can develop a self-similar collapse leading to a finite time singularity. Coincidentally, the Smoluchowski-Poisson system corresponds to a simplified version of the Keller-Segel model of bacterial populations. In this biological context, it describes the chemotactic aggregation...

The blow-up of solutions for a parabolic equation with nonlocal exponential nonlinearity is studied.

In this paper, we propose a computational model to investigate the coupling between cell’s adhesions and actin fibres and how this coupling affects cell shape and stability. To accomplish that, we take into account the successive stages of adhesion maturation from adhesion precursors to focal complexes and ultimately to focal adhesions, as well as the actin fibres evolution from growing filaments, to bundles and finally contractile stress fibres.We use substrates with discrete patterns of adhesive...

We establish new results on convergence, in strong topologies, of solutions of the parabolic-parabolic Keller-Segel system in the plane to the corresponding solutions of the parabolic-elliptic model, as a physical parameter goes to zero. Our main tools are suitable space-time estimates, implying the global existence of slowly decaying (in general, nonintegrable) solutions for these models, under a natural smallness assumption.

This review is dedicated to recent results on the 2d parabolic-elliptic Patlak-Keller-Segel model, and on its variant in higher dimensions where the diffusion is of critical porous medium type. Both of these models have a critical mass $M_c$ such that the solutions exist globally in time if the mass is less than $M_c$ and above which there are solutions which blowup in finite time. The main tools, in particular the free energy, and the idea of the methods are set out. A number of open questions are also...