Based on the coincidence degree theory of Mawhin, we get a new general existence result for the following higher-order multi-point boundary value problem at resonance $$x^{\left(n\right)}\left(t\right)=f(t,x\left(t\right),x^{\text{'}}\left(t\right),\cdots ,x^{(n-1)}\left(t\right)),t\in (0,1),x\left(0\right)=\sum _{i=1}^m{\alpha }_{i}x\left({\xi }_i\right),x^{\text{'}}\left(0\right)=\cdots =x^{(n-2)}\left(0\right)=0,x^{(n-1)}\left(1\right)=\sum _{j=1}^l{\beta }_j{x}^{(n-1)}\left({\eta }_j\right),$$ where $f:[0,1]\times {ℝ}^n\to ℝ$ is a Carathéodory function, $0<{\xi }_1<{\xi }_2<\cdots <{\xi }_m<1$, ${\alpha }_i\in ℝ$, $i=1,2,\cdots ,m$, $m\ge 2$ and $0<{\eta }_1<\cdots <{\eta }_l<1$, ${\beta }_j\in ℝ$, $j=1,\cdots ,l$, $l\ge 1$. In this paper, two of the boundary value conditions are responsible for resonance.

Nonimprovable sufficient conditions for the solvability and unique solvability of the problem $$u^{\text{'}}\left(t\right)=F\left(u\right)\left(t\right),u\left(a\right)-\lambda u\left(b\right)=h\left(u\right)$$ are established, where $F:\to$ is a continuous operator satisfying the Carathèodory conditions, $h:\to R$ is a continuous functional, and $\lambda \in$.

2000 Mathematics Subject Classification: 45G15, 26A33, 32A55, 46E15.Schauder's fixed point theorem is used to establish an existence result for an infinite system of singular integral equations in the form: (1) xi(t) = ai(t)+ ∫t0 (t − s)− α (s, x1(s), x2(s), …) ds, where i = 1,2,…, α ∈ (0,1) and t ∈ I = [0,T]. The result obtained is applied to show the solvability of an infinite system of differential equation of fractional orders.

Existence of positive solution to certain classes of singular and nonsingular third order nonlinear two point boundary value problems is examined using the idea of Topological Transversality.