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Compound Poisson approximation of word counts in DNA sequences

Sophie Schbath (2010)

ESAIM: Probability and Statistics

Identifying words with unexpected frequencies is an important problem in the analysis of long DNA sequences. To solve it, we need an approximation of the distribution of the number of occurrences N(W) of a word W. Modeling DNA sequences with m-order Markov chains, we use the Chen-Stein method to obtain Poisson approximations for two different counts. We approximate the “declumped” count of W by a Poisson variable and the number of occurrences N(W) by a compound Poisson variable. Combinatorial...

Computational schemes for two exponential servers where the first has a finite buffer

Moshe Haviv, Rita Zlotnikov (2011)

RAIRO - Operations Research - Recherche Opérationnelle

We consider a system consisting of two not necessarily identical exponential servers having a common Poisson arrival process. Upon arrival, customers inspect the first queue and join it if it is shorter than some threshold n. Otherwise, they join the second queue. This model was dealt with, among others, by Altman et al. [Stochastic Models20 (2004) 149–172]. We first derive an explicit expression for the Laplace-Stieltjes transform of the distribution underlying the arrival (renewal) process to...

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