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Planning identification experiments for cell signaling pathways: An NFκB case study

Krzysztof Fujarewicz (2010)

International Journal of Applied Mathematics and Computer Science

Mathematical modeling of cell signaling pathways has become a very important and challenging problem in recent years. The importance comes from possible applications of obtained models. It may help us to understand phenomena appearing in single cells and cell populations on a molecular level. Furthermore, it may help us with the discovery of new drug therapies. Mathematical models of cell signaling pathways take different forms. The most popular way of mathematical modeling is to use a set of nonlinear...

Poles and zeroes of nonlinear control systems

Jean-François Pommaret (2002)

Kybernetika

During the last ten years, the concepts of “poles” and “zeros” for linear control systems have been revisited by using modern commutative algebra and module theory as a powerful substitute for the theory of polynomial matrices. Very recently, these concepts have been extended to multidimensional linear control systems with constant coefficients. Our purpose is to use the methods of “algebraic analysis” in order to extend these concepts to the variable coefficients case and, as a byproduct, to the...

Polynomial controller design based on flatness

Frédéric Rotella, Francisco Javier Carillo, Mounir Ayadi (2002)

Kybernetika

By the use of flatness the problem of pole placement, which consists in imposing closed loop system dynamics can be related to tracking. Polynomial controllers for finite-dimensional linear systems can then be designed with very natural choices for high level parameters design. This design leads to a Bezout equation which is independent of the closed loop dynamics but depends only on the system model.

Polynomial systems theory applied to the analysis and design of multidimensional systems

Jari Hatonen, Raimo Ylinen (2003)

International Journal of Applied Mathematics and Computer Science

The use of a principal ideal domain structure for the analysis and design of multidimensional systems is discussed. As a first step it is shown that a lattice structure can be introduced for IO-relations generated by polynomial matrices in a signal space X (an Abelian group). It is assumed that the matrices take values in a polynomial ring F[p] where F is a field such that F[p] is a commutative subring of the ring of endomorphisms of X. After that it is analysed when a given F[p] acting on X can...

Positive 2D discrete-time linear Lyapunov systems

Przemysław Przyborowski, Tadeusz Kaczorek (2009)

International Journal of Applied Mathematics and Computer Science

Two models of positive 2D discrete-time linear Lyapunov systems are introduced. For both the models necessary and sufficient conditions for positivity, asymptotic stability, reachability and observability are established. The discussion is illustrated with numerical examples.

Positive stable realizations of fractional continuous-time linear systems

Tadeusz Kaczorek (2011)

International Journal of Applied Mathematics and Computer Science

Conditions for the existence of positive stable realizations with system Metzler matrices for fractional continuous-time linear systems are established. A procedure based on the Gilbert method for computation of positive stable realizations of proper transfer matrices is proposed. It is shown that linear minimum-phase systems with real negative poles and zeros always have positive stable realizations.

Positivity and stabilization of 2D linear systems

Tadeusz Kaczorek (2009)

Discussiones Mathematicae, Differential Inclusions, Control and Optimization

The problem of finding a gain matrix of the state-feedback of 2D linear system such that the closed-loop system is positive and asymptotically stable is formulated and solved. Necessary and sufficient conditions for the solvability of the problem are established. It is shown that the problem can be reduced to suitable linear programming problem. The proposed approach can be extended to 2D linear system described by the 2D Roesser model.

Powerful nonlinear observer associated with field-oriented control of an induction motor

Abdellah Mansouri, Mohammed Chenafa, Abderrahmane Bouhenna, Eric Etien (2004)

International Journal of Applied Mathematics and Computer Science

In this paper, we associate field-oriented control with a powerful nonlinear robust flux observer for an induction motor to show the improvement made by this observer compared with the open-loop and classical estimator used in this type of control. We implement this design strategy through an extension of a special class of nonlinear multivariable systems satisfying some regularity assumptions. We show by an extensive study that this observer is completely satisfactory at low and nominal speeds...

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