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Global Asymptotic Stability of Equilibria in Models for Virus Dynamics

J. Prüss, R. Zacher, R. Schnaubelt (2008)

Mathematical Modelling of Natural Phenomena

In this paper several models in virus dynamics with and without immune response are discussed concerning asymptotic behaviour. The case of immobile cells but diffusing viruses and T-cells is included. It is shown that, depending on the value of the basic reproductive number R0 of the virus, the corresponding equilibrium is globally asymptotically stable. If R0 < 1 then the virus-free equilibrium has this property, and in case R0 > 1 there is a unique disease equilibrium which takes over this...

Homogenization with uncertain input parameters

Luděk Nechvátal (2010)

Mathematica Bohemica

We homogenize a class of nonlinear differential equations set in highly heterogeneous media. Contrary to the usual approach, the coefficients in the equation characterizing the material properties are supposed to be uncertain functions from a given set of admissible data. The problem with uncertainties is treated by means of the worst scenario method, when we look for a solution which is critical in some sense.

Infinite systems of first order PFDEs with mixed conditions

W. Czernous (2008)

Annales Polonici Mathematici

We consider mixed problems for infinite systems of first order partial functional differential equations. An infinite number of deviating functions is permitted, and the delay of an argument may also depend on the spatial variable. A theorem on the existence of a solution and its continuous dependence upon initial boundary data is proved. The method of successive approximations is used in the existence proof. Infinite differential systems with deviated arguments and differential integral systems...

Influence of diffusion on interactions between malignant gliomas and immune system

Urszula Foryś (2010)

Applicationes Mathematicae

We analyse the influence of diffusion and space distribution of cells in a simple model of interactions between an activated immune system and malignant gliomas, among which the most aggressive one is GBM Glioblastoma Multiforme. It turns out that diffusion cannot affect stability of spatially homogeneous steady states. This suggests that there are two possible outcomes-the solution is either attracted by the positive steady state or by the semitrivial one. The semitrivial steady state describes...

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