All a b c d e f g h i j k l m n o p q r s t u v w x y z Other

Previous Page 23 Next

Displaying 441 – 460 of 816

Showing per page

Modeling the Impact of Anticancer Agents on Metastatic Spreading

S. Benzekry, N. André, A. Benabdallah, J. Ciccolini, C. Faivre, F. Hubert, D. Barbolosi (2012)

Mathematical Modelling of Natural Phenomena

Treating cancer patients with metastatic disease remains an ultimate challenge in clinical oncology. Because invasive cancer precludes or limits the use of surgery, metastatic setting is often associated with (poor) survival, rather than sustained remission, in patients with common cancers like lung, digestive or breast carcinomas. Mathematical modeling may help us better identify non detectable metastatic status to in turn optimize treatment for...

Modelli matematici a sostegno della ricerca contro il cancro

L. Preziosi (2005)

Bollettino dell'Unione Matematica Italiana

Questo articolo, a prevalente carattere di rassegna, ha lo scopo di presentare gli ambiti matematici e gli approcci metodologici utilizzati nello sviluppo di modelli matematici a sostegno della ricerca contro il cancro. La necessità di un approccio interdisciplinare e multiscala è messo in evidenza. Infine, alcuni modelli operanti alla scala macroscopica e mesoscopica sono presentati a titolo di esempio.

Modelling DNA and RNA secondary structures using matrix insertion-deletion systems

Lakshmanan Kuppusamy, Anand Mahendran (2016)

International Journal of Applied Mathematics and Computer Science

Insertion and deletion are operations that occur commonly in DNA processing and RNA editing. Since biological macromolecules can be viewed as symbols, gene sequences can be represented as strings and structures can be interpreted as languages. This suggests that the bio-molecular structures that occur at different levels can be theoretically studied by formal languages. In the literature, there is no unique grammar formalism that captures various bio-molecular structures. To overcome this deficiency,...

Modelling of Cancer Growth, Evolution and Invasion: Bridging Scales and Models

A. R.A. Anderson, K. A. Rejniak, P. Gerlee, V. Quaranta (2010)

Mathematical Modelling of Natural Phenomena

Since cancer is a complex phenomenon that incorporates events occurring on different length and time scales, therefore multiscale models are needed if we hope to adequately address cancer specific questions. In this paper we present three different multiscale individual-cell-based models, each motivated by cancer-related problems emerging from each of the spatial scales: extracellular, cellular or subcellular, but also incorporating relevant information from other levels. We apply these hybrid...

Modelling of Dynamic Problems in Biomechanics

I. Petrov, Y. Bolotskikh, A. Vasyukov (2011)

Mathematical Modelling of Natural Phenomena

This paper is devoted to solving of dynamic problems in biomechanics that require detailed study of fast processes. Numerical method of characteristics is used to model the temporal development of the processes with high accuracy.

Modelling of Plant Growth with Apical or Basal Meristem

N. Bessonov, F. Crauste, V. Volpert (2011)

Mathematical Modelling of Natural Phenomena

Plant growth occurs due to cell proliferation in the meristem. We model the case of apical meristem specific for branch growth and the case of basal meristem specific for bulbous plants and grass. In the case of apical growth, our model allows us to describe the variety of plant forms and lifetimes, endogenous rhythms and apical domination. In the case of basal growth, the spatial structure, which corresponds to the appearance of leaves, results...

Modelling Physiological and Pharmacological Control on Cell Proliferation to Optimise Cancer Treatments

J. Clairambault (2009)

Mathematical Modelling of Natural Phenomena

This review aims at presenting a synoptic, if not exhaustive, point of view on some of the problems encountered by biologists and physicians who deal with natural cell proliferation and disruptions of its physiological control in cancer disease. It also aims at suggesting how mathematicians are naturally challenged by these questions and how they might help, not only biologists to deal theoretically with biological complexity, but also physicians to optimise therapeutics, on which last point the...

Modelling the Impact of Pericyte Migration and Coverage of Vessels on the Efficacy of Vascular Disrupting Agents

S. R. McDougall, M. A.J. Chaplain, A. Stéphanou, A. R.A. Anderson (2010)

Mathematical Modelling of Natural Phenomena

Over the past decade or so, there have been a large number of modelling approaches aimed at elucidating the most important mechanisms affecting the formation of new capillaries from parent blood vessels — a process known as angiogenesis. Most studies have focussed upon the way in which capillary sprouts are initiated and migrate in response to diffusible chemical stimuli supplied by hypoxic stromal cells and leukocytes in the contexts of solid tumour...

Modelling the Spread of Infectious Diseases in Complex Metapopulations

J. Saldaña (2010)

Mathematical Modelling of Natural Phenomena

Two main approaches have been considered for modelling the dynamics of the SIS model on complex metapopulations, i.e, networks of populations connected by migratory flows whose configurations are described in terms of the connectivity distribution of nodes (patches) and the conditional probabilities of connections among classes of nodes sharing the same degree. In the first approach migration and transmission/recovery process alternate sequentially,...

Modelling Tuberculosis and Hepatitis B Co-infections

S. Bowong, J. Kurths (2010)

Mathematical Modelling of Natural Phenomena

Tuberculosis (TB) is the leading cause of death among individuals infected with the hepatitis B virus (HBV). The study of the joint dynamics of HBV and TB present formidable mathematical challenges due to the fact that the models of transmission are quite distinct. We formulate and analyze a deterministic mathematical model which incorporates of the co-dynamics of hepatitis B and tuberculosis. Two sub-models, namely: HBV-only and TB-only sub-models...

Currently displaying 441 – 460 of 816