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Modelling the Impact of Pericyte Migration and Coverage of Vessels on the Efficacy of Vascular Disrupting Agents

S. R. McDougall, M. A.J. Chaplain, A. Stéphanou, A. R.A. Anderson (2010)

Mathematical Modelling of Natural Phenomena

Over the past decade or so, there have been a large number of modelling approaches aimed at elucidating the most important mechanisms affecting the formation of new capillaries from parent blood vessels — a process known as angiogenesis. Most studies have focussed upon the way in which capillary sprouts are initiated and migrate in response to diffusible chemical stimuli supplied by hypoxic stromal cells and leukocytes in the contexts of solid tumour...

More pressure in the finite element discretization of the Stokes problem

Christine Bernardi, Frédéric Hecht (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

For the Stokes problem in a two- or three-dimensional bounded domain, we propose a new mixed finite element discretization which relies on a nonconforming approximation of the velocity and a more accurate approximation of the pressure. We prove that the velocity and pressure discrete spaces are compatible, in the sense that they satisfy an inf-sup condition of Babuška and Brezzi type, and we derive some error estimates.

Mortar finite element discretization of a model coupling Darcy and Stokes equations

Christine Bernardi, Tomás Chacón Rebollo, Frédéric Hecht, Zoubida Mghazli (2008)

ESAIM: Mathematical Modelling and Numerical Analysis

As a first draft of a model for a river flowing on a homogeneous porous ground, we consider a system where the Darcy and Stokes equations are coupled via appropriate matching conditions on the interface. We propose a discretization of this problem which combines the mortar method with standard finite elements, in order to handle separately the flow inside and outside the porous medium. We prove a priori and a posteriori error estimates for the resulting discrete problem. Some numerical experiments...

Mucus dynamics subject to air and wall motion*

S. Enault, D. Lombardi, P. Poncet, M. Thiriet (2010)

ESAIM: Proceedings

This study presents a numerical investigation of basic interactions between respiratory mucus motion, air circulation and epithelium ciliated cells vibration. One focuses on identification of meaningful rheological parameters, physiological and numerical simulation dimensioning. These preliminary results are crucial before the study of more general configurations of respiratory mucus motion. The numerical study presented in this work aims at providing...

Multicomponent models in nuclear astrophysics

Bernard Ducomet (2008)

Banach Center Publications

We consider hydrodynamical models describing the evolution of a gaseous star in which the presence of thermonuclear reactions between several species leads to a multicomponent formulation. In the case of binary mixtures, recent 3D results are evoked. In the one-dimensional situation, we can prove global estimates and stabilization for some simplified model.

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