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Mathematical and numerical modeling of early atherosclerotic lesions***

Vincent Calvez, Jean Gabriel Houot, Nicolas Meunier, Annie Raoult, Gabriela Rusnakova (2010)

ESAIM: Proceedings

This article is devoted to the construction of a mathematical model describing the early formation of atherosclerotic lesions. The early stage of atherosclerosis is an inflammatory process that starts with the penetration of low density lipoproteins in the intima and with their oxidation. This phenomenon is closely linked to the local blood flow dynamics. Extending a previous work [5] that was mainly restricted to a one-dimensional setting, we couple...

Mathematical modeling and simulation of flow in domains separated by leaky semipermeable membrane including osmotic effect

Jaroslav Hron, Maria Neuss-Radu, Petra Pustějovská (2011)

Applications of Mathematics

In this paper, we propose a mathematical model for flow and transport processes of diluted solutions in domains separated by a leaky semipermeable membrane. We formulate transmission conditions for the flow and the solute concentration across the membrane which take into account the property of the membrane to partly reject the solute, the accumulation of rejected solute at the membrane, and the influence of the solute concentration on the volume flow, known as osmotic effect. The model is solved...

Maximal regularity and viscous incompressible flows with free interface

Senjo Shimizu (2008)

Banach Center Publications

We consider a free interface problem for the Navier-Stokes equations. We obtain local in time unique existence of solutions to this problem for any initial data and external forces, and global in time unique existence of solutions for sufficiently small initial data. Thanks to global in time L p - L q maximal regularity of the linearized problem, we can prove a global in time existence and uniqueness theorem by the contraction mapping principle.

Mean field limit for the one dimensional Vlasov-Poisson equation

Maxime Hauray (2012/2013)

Séminaire Laurent Schwartz — EDP et applications

We consider systems of N particles in dimension one, driven by pair Coulombian or gravitational interactions. When the number of particles goes to infinity in the so called mean field scaling, we formally expect convergence towards the Vlasov-Poisson equation. Actually a rigorous proof of that convergence was given by Trocheris in [Tro86]. Here we shall give a simpler proof of this result, and explain why it implies the so-called “Propagation of molecular chaos”. More precisely, both results will...

Medical image – based computational model of pulsatile flow in saccular aneurisms

Stéphanie Salmon, Marc Thiriet, Jean-Frédéric Gerbeau (2003)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

Saccular aneurisms, swelling of a blood vessel, are investigated in order (i) to estimate the development risk of the wall lesion, before and after intravascular treatment, assuming that the pressure is the major factor, and (ii) to better plan medical interventions. Numerical simulations, using the finite element method, are performed in three-dimensional aneurisms. Computational meshes are derived from medical imaging data to take into account both between-subject and within-subject anatomical...

Medical image – based computational model of pulsatile flow in saccular aneurisms

Stéphanie Salmon, Marc Thiriet, Jean-Frédéric Gerbeau (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

Saccular aneurisms, swelling of a blood vessel, are investigated in order (i) to estimate the development risk of the wall lesion, before and after intravascular treatment, assuming that the pressure is the major factor, and (ii) to better plan medical interventions. Numerical simulations, using the finite element method, are performed in three-dimensional aneurisms. Computational meshes are derived from medical imaging data to take into account both between-subject and within-subject anatomical...

Modelling of Cancer Growth, Evolution and Invasion: Bridging Scales and Models

A. R.A. Anderson, K. A. Rejniak, P. Gerlee, V. Quaranta (2010)

Mathematical Modelling of Natural Phenomena

Since cancer is a complex phenomenon that incorporates events occurring on different length and time scales, therefore multiscale models are needed if we hope to adequately address cancer specific questions. In this paper we present three different multiscale individual-cell-based models, each motivated by cancer-related problems emerging from each of the spatial scales: extracellular, cellular or subcellular, but also incorporating relevant information from other levels. We apply these hybrid...

Modelling of convective phenomena in forest fire.

M.ª Isabel Asensio, Luis Ferragut, Jacques Simon (2002)

RACSAM

We present a model coupling the fire propagation equations in a bidimensional domain representing the surface, and the air movement equations in a three dimensional domain representing an air layer. As the air layer thickness is small compared with its length, an asymptotic analysis gives a three dimensional convective model governed by a bidimensional equation verified by a stream function. We also present the numerical simulations of these equations.

Modelling of miscible liquids with the Korteweg stress

Ilya Kostin, Martine Marion, Rozenn Texier-Picard, Vitaly A. Volpert (2003)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

When two miscible fluids, such as glycerol (glycerin) and water, are brought in contact, they immediately diffuse in each other. However if the diffusion is sufficiently slow, large concentration gradients exist during some time. They can lead to the appearance of an “effective interfacial tension”. To study these phenomena we use the mathematical model consisting of the diffusion equation with convective terms and of the Navier-Stokes equations with the Korteweg stress. We prove the global existence...

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