All a b c d e f g h i j k l m n o p q r s t u v w x y z Other

Page 1 Next

Displaying 1 – 20 of 66

Showing per page

Sampling properties of estimators of nucleotide diversity at discovered SNP sites

Alexander Renwick, Penelope Bonnen, Dimitra Trikka, David Nelson, Ranajit Chakraborty, Marek Kimmel (2003)

International Journal of Applied Mathematics and Computer Science

SNP sites are generally discovered by sequencing regions of the human genome in a limited number of individuals. This may leave SNP sites present in the region, but containing rare mutant nucleotides, undetected. Consequently, estimates of nucleotide diversity obtained from assays of detected SNP sites are biased. In this research we present a statistical model of the SNP discovery process, which is used to evaluate the extent of this bias. This model involves the symmetric Beta distribution of...

Scaling of Stochasticity in Dengue Hemorrhagic Fever Epidemics

M. Aguiar, B.W. Kooi, J. Martins, N. Stollenwerk (2012)

Mathematical Modelling of Natural Phenomena

In this paper we analyze the stochastic version of a minimalistic multi-strain model, which captures essential differences between primary and secondary infections in dengue fever epidemiology, and investigate the interplay between stochasticity, seasonality and import. The introduction of stochasticity is needed to explain the fluctuations observed in some of the available data sets, revealing a scenario where noise and complex deterministic skeleton...

Segmentation of breast cancer fine needle biopsy cytological images

Maciej Hrebień, Piotr Steć, Tomasz Nieczkowski, Andrzej Obuchowicz (2008)

International Journal of Applied Mathematics and Computer Science

This paper describes three cytological image segmentation methods. The analysis includes the watershed algorithm, active contouring and a cellular automata GrowCut method. One can also find here a description of image pre-processing, Hough transform based pre-segmentation and an automatic nuclei localization mechanism used in our approach. Preliminary experimental results collected on a benchmark database present the quality of the methods in the analyzed issue. The discussion of common errors and...

Segmentation of MRI data by means of nonlinear diffusion

Radomír Chabiniok, Radek Máca, Michal Beneš, Jaroslav Tintěra (2013)

Kybernetika

The article focuses on the application of the segmentation algorithm based on the numerical solution of the Allen-Cahn non-linear diffusion partial differential equation. This equation is related to the motion of curves by mean curvature. It exhibits several suitable mathematical properties including stable solution profile. This allows the user to follow accurately the position of the segmentation curve by bringing it quickly to the vicinity of the segmented object and by approaching the details...

Segregation of Flowing Blood: Mathematical Description

A. Tokarev, G. Panasenko, F. Ataullakhanov (2011)

Mathematical Modelling of Natural Phenomena

Blood rheology is completely determined by its major corpuscles which are erythrocytes, or red blood cells (RBCs). That is why understanding and correct mathematical description of RBCs behavior in blood is a critical step in modelling the blood dynamics. Various phenomena provided by RBCs such as aggregation, deformation, shear-induced diffusion and non-uniform radial distribution affect the passage of blood through the vessels. Hence, they have...

Selecting differentially expressed genes for colon tumor classification

Krzysztof Fujarewicz, Małgorzata Wiench (2003)

International Journal of Applied Mathematics and Computer Science

DNA microarrays provide a new technique of measuring gene expression, which has attracted a lot of research interest in recent years. It was suggested that gene expression data from microarrays (biochips) can be employed in many biomedical areas, e.g., in cancer classification. Although several, new and existing, methods of classification were tested, a selection of proper (optimal) set of genes, the expressions of which can serve during classification, is still an open problem. Recently we have...

Self-Assembly of Icosahedral Viral Capsids: the Combinatorial Analysis Approach

R. Kerner (2011)

Mathematical Modelling of Natural Phenomena

An analysis of all possible icosahedral viral capsids is proposed. It takes into account the diversity of coat proteins and their positioning in elementary pentagonal and hexagonal configurations, leading to definite capsid size. We show that the self-organization of observed capsids during their production implies a definite composition and configuration of elementary building blocks. The exact number of different protein dimers is related to the...

Self-similarity in chemotaxis systems

Yūki Naito, Takashi Suzuki (2008)

Colloquium Mathematicae

We consider a system which describes the scaling limit of several chemotaxis systems. We focus on self-similarity, and review some recent results on forward and backward self-similar solutions to the system.

Simulating Kinetic Processes in Time and Space on a Lattice

J. P. Gill, K. M. Shaw, B. L. Rountree, C. E. Kehl, H. J. Chiel (2011)

Mathematical Modelling of Natural Phenomena

We have developed a chemical kinetics simulation that can be used as both an educational and research tool. The simulator is designed as an accessible, open-source project that can be run on a laptop with a student-friendly interface. The application can potentially be scaled to run in parallel for large simulations. The simulation has been successfully used in a classroom setting for teaching basic electrochemical properties. We have shown that...

Simulation of electrophysiological waves with an unstructured finite element method

Yves Bourgault, Marc Ethier, Victor G. LeBlanc (2003)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

Bidomain models are commonly used for studying and simulating electrophysiological waves in the cardiac tissue. Most of the time, the associated PDEs are solved using explicit finite difference methods on structured grids. We propose an implicit finite element method using unstructured grids for an anisotropic bidomain model. The impact and numerical requirements of unstructured grid methods is investigated using a test case with re-entrant waves.

Simulation of Electrophysiological Waves with an Unstructured Finite Element Method

Yves Bourgault, Marc Ethier, Victor G. LeBlanc (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

Bidomain models are commonly used for studying and simulating electrophysiological waves in the cardiac tissue. Most of the time, the associated PDEs are solved using explicit finite difference methods on structured grids. We propose an implicit finite element method using unstructured grids for an anisotropic bidomain model. The impact and numerical requirements of unstructured grid methods is investigated using a test case with re-entrant waves.

Singular Perturbation Analysis of Travelling Waves for a Model in Phytopathology

J. B. Burie, A. Calonnec, A. Ducrot (2010)

Mathematical Modelling of Natural Phenomena

We investigate the structure of travelling waves for a model of a fungal disease propagating over a vineyard. This model is based on a set of ODEs of the SIR-type coupled with two reaction-diffusion equations describing the dispersal of the spores produced by the fungus inside and over the vineyard. An estimate of the biological parameters in the model suggests to use a singular perturbation analysis. It allows us to compute the speed and the profile of the travelling waves. The analytical results...

Singular Perturbations For Heart Image Segmentation Tracking

J. Pousin (2009)

Mathematical Modelling of Natural Phenomena

In this note we give a result of convergence when time goes to infinity for a quasi static linear elastic model, the elastic tensor of which vanishes at infinity. This method is applied to segmentation of medical images, and improves the 'elastic deformable template' model introduced previously.

Currently displaying 1 – 20 of 66

Page 1 Next