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Skupinový screening

Christian Genest, Christiane Rousseau (2021)

Pokroky matematiky, fyziky a astronomie

Skupinový screening je nezbytnou součástí boje proti šíření koronaviru. Jak ale čelit možnému nedostatku činidel a materiálu? Tím, že budeme provádět testy na bázi promíchání vzorků a využijeme přitom matematiku.

Small amplitude homogenization applied to models of non-periodic fibrous materials

David Manceau (2007)

ESAIM: Mathematical Modelling and Numerical Analysis

In this paper, we compare a biomechanics empirical model of the heart fibrous structure to two models obtained by a non-periodic homogenization process. To this end, the two homogenized models are simplified using the small amplitude homogenization procedure of Tartar, both in conduction and in elasticity. A new small amplitude homogenization expansion formula for a mixture of anisotropic elastic materials is also derived and allows us to obtain a third simplified model.

Some necessary and sufficient conditions for the output controllability of temporal Boolean control networks

Yang Liu, Jianquan Lu, Bo Wu (2014)

ESAIM: Control, Optimisation and Calculus of Variations

This paper investigates the output controllability problem of temporal Boolean networks with inputs (control nodes) and outputs (controlled nodes). A temporal Boolean network is a logical dynamic system describing cellular networks with time delays. Using semi-tensor product of matrices, the temporal Boolean networks can be converted into discrete time linear dynamic systems. Some necessary and sufficient conditions on the output controllability via two kinds of inputs are obtained by providing...

Some Parameter Estimation Issues in Functional-Structural Plant Modelling

P.-H. Cournède, V. Letort, A. Mathieu, M. Z. Kang, S. Lemaire, S. Trevezas, F. Houllier, P. de Reffye (2011)

Mathematical Modelling of Natural Phenomena

The development of functional-structural plant models has opened interesting perspectives for a better understanding of plant growth as well as for potential applications in breeding or decision aid in farm management. Parameterization of such models is however a difficult issue due to the complexity of the involved biological processes and the interactions between these processes. The estimation of parameters from experimental data by inverse methods...

Spatial Dynamics of Contact-Activated Fibrin Clot Formation in vitro and in silico in Haemophilia B: Effects of Severity and Ahemphil B Treatment

A. A. Tokarev, Yu. V. Krasotkina, M. V. Ovanesov, M. A. Panteleev, M. A. Azhigirova, V. A. Volpert, F. I. Ataullakhanov, A. A. Butilin (2010)

Mathematical Modelling of Natural Phenomena

Spatial dynamics of fibrin clot formation in non-stirred system activated by glass surface was studied as a function of FIX activity. Haemophilia B plasma was obtained from untreated patients with different levels of FIX deficiency and from severe haemophilia B patient treated with FIX concentrate (Ahemphil B) during its clearance with half-life t1/2=12 hours. As reported previously (Ataullakhanov et al. Biochim Biophys Acta 1998; 1425: 453-468), clot growth in space showed two distinct phases:...

Spatiotemporal Dynamics in a Spatial Plankton System

R. K. Upadhyay, W. Wang, N. K. Thakur (2010)

Mathematical Modelling of Natural Phenomena

In this paper, we investigate the complex dynamics of a spatial plankton-fish system with Holling type III functional responses. We have carried out the analytical study for both one and two dimensional system in details and found out a condition for diffusive instability of a locally stable equilibrium. Furthermore, we present a theoretical analysis of processes of pattern formation that involves organism distribution and their interaction of spatially...

Spatio-Temporal Modelling of the p53–mdm2 Oscillatory System

K. E. Gordon, I. M.M. van Leeuwen, S. Laín, M. A.J. Chaplain (2009)

Mathematical Modelling of Natural Phenomena

In this paper we investigate the role of spatial effects in determining the dynamics of a subclass of signalling pathways characterised by their ability to demonstrate oscillatory behaviour. To this end, we formulate a simple spatial model of the p53 network that accounts for both a negative feedback and a transcriptional delay. We show that the formation of protein density patterns can depend on the shape of the cell, position of the nucleus, and the protein diffusion rates. The temporal...

Stability Analysis of Cell Dynamics in Leukemia

H. Özbay, C. Bonnet, H. Benjelloun, J. Clairambault (2012)

Mathematical Modelling of Natural Phenomena

In order to better understand the dynamics of acute leukemia, and in particular to find theoretical conditions for the efficient delivery of drugs in acute myeloblastic leukemia, we investigate stability of a system modeling its cell dynamics. The overall system is a cascade connection of sub-systems consisting of distributed delays and static nonlinear feedbacks. Earlier results on local asymptotic stability are improved by the analysis of the linearized...

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