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Reaction-Difusion Model of Early Carcinogenesis: The Effects of Influx of Mutated Cells

Anna Marciniak-Czochra, Marek Kimmel (2008)

Mathematical Modelling of Natural Phenomena

In this paper we explore a new model of field carcinogenesis, inspired by lung cancer precursor lesions, which includes dynamics of a spatially distributed population of pre-cancerous cells c(t, x), constantly supplied by an influx μ of mutated normal cells. Cell proliferation is controlled by growth factor molecules bound to cells, b(t, x). Free growth factor molecules g(t, x) are produced by precancerous cells and may diffuse before they become bound to other cells. The purpose of modelling is...

Recent progress in attractors for quintic wave equations

Anton Savostianov, Sergey Zelik (2014)

Mathematica Bohemica

We report on new results concerning the global well-posedness, dissipativity and attractors for the quintic wave equations in bounded domains of 3 with damping terms of the form ( - Δ x ) θ t u , where θ = 0 or θ = 1 / 2 . The main ingredient of the work is the hidden extra regularity of solutions that does not follow from energy estimates. Due to the extra regularity of solutions existence of a smooth attractor then follows from the smoothing property when θ = 1 / 2 . For θ = 0 existence of smooth attractors is more complicated and follows...

Recent results on stationary critical Kirchhoff systems in closed manifolds

Emmanuel Hebey, Pierre-Damien Thizy (2013/2014)

Séminaire Laurent Schwartz — EDP et applications

We report on results we recently obtained in Hebey and Thizy [11, 12] for critical stationary Kirchhoff systems in closed manifolds. Let ( M n , g ) be a closed n -manifold, n 3 . The critical Kirchhoff systems we consider are written as a + b j = 1 p M | u j | 2 d v g Δ g u i + j = 1 p A i j u j = U 2 - 2 u i for all i = 1 , , p , where Δ g is the Laplace-Beltrami operator, A is a C 1 -map from M into the space M s p ( ) of symmetric p × p matrices with real entries, the A i j ’s are the components of A , U = ( u 1 , , u p ) , | U | : M is the Euclidean norm of U , 2 = 2 n n - 2 is the critical Sobolev exponent, and we require that u i 0 in M for all i = 1 , , p . We...

Recovery of an unknown flux in parabolic problems with nonstandard boundary conditions: Error estimates

Marián Slodička (2003)

Applications of Mathematics

In this paper, we consider a 2nd order semilinear parabolic initial boundary value problem (IBVP) on a bounded domain Ω N , with nonstandard boundary conditions (BCs). More precisely, at some part of the boundary we impose a Neumann BC containing an unknown additive space-constant α ( t ) , accompanied with a nonlocal (integral) Dirichlet side condition. We design a numerical scheme for the approximation of a weak solution to the IBVP and derive error estimates for the approximation of the solution u and...

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