All a b c d e f g h i j k l m n o p q r s t u v w x y z Other

Previous Page 2 Next

Displaying 21 – 40 of 107

Showing per page

Mathematical modeling of antigenicity for HIV dynamics

François Dubois, Hervé V.J. Le Meur, Claude Reiss (2010)

MathematicS In Action

This contribution is devoted to a new model of HIV multiplication motivated by the patent of one of the authors. We take into account the antigenic diversity through what we define “antigenicity”, whether of the virus or of the adapted lymphocytes. We model the interaction of the immune system and the viral strains by two processes. On the one hand, the presence of a given viral quasi-species generates antigenically adapted lymphocytes. On the other hand, the lymphocytes kill only viruses for which...

Mathematical Modeling of Leukemogenesis and Cancer Stem Cell Dynamics

T. Stiehl, A. Marciniak-Czochra (2012)

Mathematical Modelling of Natural Phenomena

The cancer stem cell hypothesis has evolved to one of the most important paradigms in biomedical research. During recent years evidence has been accumulating for the existence of stem cell-like populations in different cancers, especially in leukemias. In the current work we propose a mathematical model of cancer stem cell dynamics in leukemias. We apply the model to compare cellular properties of leukemic stem cells to those of their benign counterparts....

Mathematical modeling of the competition between acquired immunity and cancer

Mikhail Kolev (2003)

International Journal of Applied Mathematics and Computer Science

In this paper we propose and analyse a model of the competition between cancer and the acquired immune system. The model is a system of integro-differential bilinear equations. The role of the humoral response is analyzed. The simulations are related to the immunotherapy of tumors with antibodies.

Mathematical Modelling of Cancer Stem Cells Population Behavior

E. Beretta, V. Capasso, N. Morozova (2012)

Mathematical Modelling of Natural Phenomena

Recent discovery of cancer stem cells in tumorigenic tissues has raised many questions about their nature, origin, function and their behavior in cell culture. Most of current experiments reporting a dynamics of cancer stem cell populations in culture show the eventual stability of the percentages of these cell populations in the whole population of cancer cells, independently of the starting conditions. In this paper we propose a mathematical model...

Mathematical modelling of molecule evolution in protocells

Dariusz Myszor, Krzysztof A. Cyran (2013)

International Journal of Applied Mathematics and Computer Science

In this article, we analyse the process of the emergence of RNA polynucleotides located in an enclosed environment, at an early stage of the RNA world. Therefore we prepared a mathematical model, composed of a set of differential equations, which simulates the behaviour of an early biological system bounded by a protocell membrane. There is evidence that enclosed environments were available on the primordial Earth. There are also experimental proofs that RNA strands can develop in these formations....

Mathematical Modelling of Tumour Dormancy

K. M. Page (2009)

Mathematical Modelling of Natural Phenomena

Many tumours undergo periods in which they apparently do not grow but remain at a roughly constant size for extended periods. This is termed tumour dormancy. The mechanisms responsible for dormancy include failure to develop an internal blood supply, individual tumour cells exiting the cell cycle and a balance between the tumour and the immune response to it. Tumour dormancy is of considerable importance in the natural history of cancer. In many cancers, and in particular in breast cancer, recurrence...

Mathematical Models of Dividing Cell Populations: Application to CFSE Data

H.T. Banks, W. Clayton Thompson (2012)

Mathematical Modelling of Natural Phenomena

Flow cytometric analysis using intracellular dyes such as CFSE is a powerful experimental tool which can be used in conjunction with mathematical modeling to quantify the dynamic behavior of a population of lymphocytes. In this survey we begin by providing an overview of the mathematically relevant aspects of the data collection procedure. We then present an overview of the large body of mathematical models, along with their assumptions and uses,...

Mathematical models of tumor growth systems

Takashi Suzuki (2012)

Mathematica Bohemica

We study a class of parabolic-ODE systems modeling tumor growth, its mathematical modeling and the global in time existence of the solution obtained by the method of Lyapunov functions.

Currently displaying 21 – 40 of 107