Mathematical models of tumor growth systems
We study a class of parabolic-ODE systems modeling tumor growth, its mathematical modeling and the global in time existence of the solution obtained by the method of Lyapunov functions.
We study a class of parabolic-ODE systems modeling tumor growth, its mathematical modeling and the global in time existence of the solution obtained by the method of Lyapunov functions.
The paper is devoted to mathematical modelling and numerical computations of a nonstationary free boundary problem. The model is based on processes of molecular diffusion of some products of chemical decomposition of a solid organic substance concentrated in bottom sediments. It takes into account non-stationary multi-component and multi-stage chemical decomposition of organic substances and the processes of sorption desorption under aerobic and anaerobic conditions. Such a model allows one to...
We consider the early carcinogenesis model originally proposed as a deterministic reaction-diffusion system. The model has been conceived to explore the spatial effects stemming from growth regulation of pre-cancerous cells by diffusing growth factor molecules. The model exhibited Turing instability producing transient spatial spikes in cell density, which might be considered a model counterpart of emerging foci of malignant cells. However, the process...
We study the unsaturated flow of an incompressible liquid carrying a bacterial population through a porous medium contaminated with some pollutant. The biomass grows feeding on the pollutant and affecting at the same time all the physics of the flow. We formulate a mathematical model in a one-dimensional setting and we prove an existence theorem for it. The so-called fluid media scaling approach, often used in the literature, is discussed and its limitations are pointed out on the basis of a specific...
We present a model coupling the fire propagation equations in a bidimensional domain representing the surface, and the air movement equations in a three dimensional domain representing an air layer. As the air layer thickness is small compared with its length, an asymptotic analysis gives a three dimensional convective model governed by a bidimensional equation verified by a stream function. We also present the numerical simulations of these equations.
Plant growth occurs due to cell proliferation in the meristem. We model the case of apical meristem specific for branch growth and the case of basal meristem specific for bulbous plants and grass. In the case of apical growth, our model allows us to describe the variety of plant forms and lifetimes, endogenous rhythms and apical domination. In the case of basal growth, the spatial structure, which corresponds to the appearance of leaves, results...
Bacillus subtilis swarms rapidly over the surface of a synthetic medium creating remarkable hyperbranched dendritic communities. Models to reproduce such effects have been proposed under the form of parabolic Partial Differential Equations representing the dynamics of the active cells (both motile and multiplying), the passive cells (non-motile and non-growing) and nutrient concentration. We test the numerical behavior of such models and compare...
In [A. Genadot and M. Thieullen, Averaging for a fully coupled piecewise-deterministic markov process in infinite dimensions. Adv. Appl. Probab. 44 (2012) 749–773], the authors addressed the question of averaging for a slow-fast Piecewise Deterministic Markov Process (PDMP) in infinite dimensions. In the present paper, we carry on and complete this work by the mathematical analysis of the fluctuations of the slow-fast system around the averaged limit. A central limit theorem is derived and the associated...
Multiscale stochastic homogenization is studied for convection-diffusion problems. More specifically, we consider the asymptotic behaviour of a sequence of realizations of the form . It is shown, under certain structure assumptions on the random vector field and the random map , that the sequence of solutions converges in the sense of G-convergence of parabolic operators to the solution of the homogenized problem .