Corresponding to the wellposedness result [2] for the classical 3-D Navier-Stokes equations with initial data in the scaling invariant Besov space, here we consider a similar problem for the 3-D anisotropic Navier-Stokes equations where the vertical viscosity is zero. In order to do so, we first introduce the Besov-Sobolev type spaces, and Then with initial data in the scaling invariant space we prove the global wellposedness for provided the norm of initial data is small enough compared...