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Reliable numerical modelling of malaria propagation

István Faragó, Miklós Emil Mincsovics, Rahele Mosleh (2018)

Applications of Mathematics

We investigate biological processes, particularly the propagation of malaria. Both the continuous and the numerical models on some fixed mesh should preserve the basic qualitative properties of the original phenomenon. Our main goal is to give the conditions for the discrete (numerical) models of the malaria phenomena under which they possess some given qualitative property, namely, to be between zero and one. The conditions which guarantee this requirement are related to the time-discretization...

Speed-up of reaction-diffusion fronts by a line of fast diffusion

Henri Berestycki, Anne-Charline Coulon, Jean-Michel Roquejoffre, Luca Rossi (2013/2014)

Séminaire Laurent Schwartz — EDP et applications

In these notes, we discuss a new model, proposed by H. Berestycki, J.-M. Roquejoffre and L. Rossi, to describe biological invasions in the plane when a strong diffusion takes place on a line. This model seems relevant to account for the effects of roads on the spreading of invasive species. In what follows, the diffusion on the line will either be modelled by the Laplacian operator, or the fractional Laplacian of order less than 1. Of interest to us is the asymptotic speed of spreading in the direction...

Stability for a diffusive delayed predator-prey model with modified Leslie-Gower and Holling-type II schemes

Yanling Tian (2014)

Applications of Mathematics

A diffusive delayed predator-prey model with modified Leslie-Gower and Holling-type II schemes is considered. Local stability for each constant steady state is studied by analyzing the eigenvalues. Some simple and easily verifiable sufficient conditions for global stability are obtained by virtue of the stability of the related FDE and some monotonous iterative sequences. Numerical simulations and reasonable biological explanations are carried out to illustrate the main results and the justification...

Stabilization in degenerate parabolic equations in divergence form and application to chemotaxis systems

Sachiko Ishida, Tomomi Yokota (2023)

Archivum Mathematicum

This paper presents a stabilization result for weak solutions of degenerate parabolic equations in divergence form. More precisely, the result asserts that the global-in-time weak solution converges to the average of the initial data in some topology as time goes to infinity. It is also shown that the result can be applied to a degenerate parabolic-elliptic Keller-Segel system.

Systems of reaction-diffusion equations with spatially distributed hysteresis

Pavel Gurevich, Sergey Tikhomirov (2014)

Mathematica Bohemica

We study systems of reaction-diffusion equations with discontinuous spatially distributed hysteresis on the right-hand side. The input of the hysteresis is given by a vector-valued function of space and time. Such systems describe hysteretic interaction of non-diffusive (bacteria, cells, etc.) and diffusive (nutrient, proteins, etc.) substances leading to formation of spatial patterns. We provide sufficient conditions under which the problem is well posed in spite of the assumed discontinuity of...

The Effect of Bacteria on Epidermal Wound Healing

E. Agyingi, S. Maggelakis, D. Ross (2010)

Mathematical Modelling of Natural Phenomena

Epidermal wound healing is a complex process that repairs injured tissue. The complexity of this process increases when bacteria are present in a wound; the bacteria interaction determines whether infection sets in. Because of underlying physiological problems infected wounds do not follow the normal healing pattern. In this paper we present a mathematical model of the healing of both infected and uninfected wounds. At the core of our model is an...

The Intersection of Theory and Application in Elucidating Pattern Formation in Developmental Biology

H. G. Othmer, K. Painter, D. Umulis, C. Xue (2009)

Mathematical Modelling of Natural Phenomena

We discuss theoretical and experimental approaches to three distinct developmental systems that illustrate how theory can influence experimental work and vice-versa. The chosen systems – Drosophila melanogaster, bacterial pattern formation, and pigmentation patterns – illustrate the fundamental physical processes of signaling, growth and cell division, and cell movement involved in pattern formation and development. These systems exemplify the current state of theoretical and experimental understanding...

The Rothe method for the McKendrick-von Foerster equation

Henryk Leszczyński, Piotr Zwierkowski (2013)

Czechoslovak Mathematical Journal

We present the Rothe method for the McKendrick-von Foerster equation with initial and boundary conditions. This method is well known as an abstract Euler scheme in extensive literature, e.g. K. Rektorys, The Method of Discretization in Time and Partial Differential Equations, Reidel, Dordrecht, 1982. Various Banach spaces are exploited, the most popular being the space of bounded and continuous functions. We prove the boundedness of approximate solutions and stability of the Rothe method in L ∞ and...

Transport Equation Reduction for a Mathematical Model in Plant Growth

S. Boujena, A. Chiboub, J. Pousin (2011)

Mathematical Modelling of Natural Phenomena

In this article a variational reduction method, how to handle the case of heterogenous domains for the Transport equation, is presented. This method allows to get rid of the restrictions on the size of time steps due to the thin parts of the domain. In the thin part of the domain, only a differential problem, with respect to the space variable, is to be approximated numerically. Numerical results are presented with a simple example. The variational...

Variational Reduction for the Transport Equation in a Multiple Branching Plants Growth Model

S. Boujena, A. Chiboub, J. Pousin (2010)

Mathematical Modelling of Natural Phenomena

Plant growth depends essentially on nutrients coming from the roots and metabolites produced by the plant. Appearance of new branches is determined by concentrations of certain plant hormones. The most important of them are Auxin and Cytokinin. Auxin is produced in the growing, Cytokinin in either roots or in growing parts. Many dynamical models of this phenomena have been studied in [1]. In [5], the authors deal with one branch model. In this work,...

Vessel Wall Models for Simulation of Atherosclerotic Vascular Networks

Yu. Vassilevski, S. Simakov, V. Salamatova, Yu. Ivanov, T. Dobroserdova (2011)

Mathematical Modelling of Natural Phenomena

There are two mathematical models of elastic walls of healthy and atherosclerotic blood vessels developed and studied. The models are included in a numerical model of global blood circulation via recovery of the vessel wall state equation. The joint model allows us to study the impact of arteries atherosclerotic disease of a set of arteries on regional haemodynamics.

Waves of Autocrine Signaling in Patterned Epithelia

C. B. Muratov, S. Y. Shvartsman (2010)

Mathematical Modelling of Natural Phenomena

A biophysical model describing long-range cell-to-cell communication by a diffusible signal mediated by autocrine loops in developing epithelia in the presence of a morphogenetic pre-pattern is introduced. Under a number of approximations, the model reduces to a particular kind of bistable reaction-diffusion equation with strong heterogeneity. In the case of the heterogeneity in the form of a long strip a detailed analysis of signal propagation is...

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