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Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers

Sébastien Benzekry (2012)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

We introduce a phenomenological model for anti-angiogenic therapy in the treatment of metastatic cancers. It is a structured transport equation with a nonlocal boundary condition describing the evolution of the density of metastases that we analyze first at the continuous level. We present the numerical analysis of a lagrangian scheme based on the characteristics whose convergence establishes existence of solutions. Then we prove an error estimate and use the model to perform interesting simulations...

Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers

Sébastien Benzekry (2012)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

We introduce a phenomenological model for anti-angiogenic therapy in the treatment of metastatic cancers. It is a structured transport equation with a nonlocal boundary condition describing the evolution of the density of metastases that we analyze first at the continuous level. We present the numerical analysis of a lagrangian scheme based on the characteristics whose convergence establishes existence of solutions. Then we prove an error estimate and use the model to perform interesting simulations...

Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers

Sébastien Benzekry (2011)

ESAIM: Mathematical Modelling and Numerical Analysis

We introduce a phenomenological model for anti-angiogenic therapy in the treatment of metastatic cancers. It is a structured transport equation with a nonlocal boundary condition describing the evolution of the density of metastases that we analyze first at the continuous level. We present the numerical analysis of a lagrangian scheme based on the characteristics whose convergence establishes existence of solutions. Then we prove an error estimate and use the model to perform interesting simulations...

Mathematical and numerical analysis of a stratigraphic model

Véronique Gervais, Roland Masson (2004)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

In this paper, we consider a multi-lithology diffusion model used in stratigraphic modelling to simulate large scale transport processes of sediments described as a mixture of L lithologies. This model is a simplified one for which the surficial fluxes are proportional to the slope of the topography and to a lithology fraction with unitary diffusion coefficients. The main unknowns of the system are the sediment thickness h , the L surface concentrations c i s in lithology i of the sediments at the top...

Mathematical and numerical analysis of a stratigraphic model

Véronique Gervais, Roland Masson (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

In this paper, we consider a multi-lithology diffusion model used in stratigraphic modelling to simulate large scale transport processes of sediments described as a mixture of L lithologies. This model is a simplified one for which the surficial fluxes are proportional to the slope of the topography and to a lithology fraction with unitary diffusion coefficients. The main unknowns of the system are the sediment thickness h, the L surface concentrations c i s in lithology i of the sediments at the...

Mathematical and numerical analysis of radiative heat transfer in semi-transparent media

Yao-Chuang Han, Yu-Feng Nie, Zhan-Bin Yuan (2019)

Applications of Mathematics

This paper is concerned with mathematical and numerical analysis of the system of radiative integral transfer equations. The existence and uniqueness of solution to the integral system is proved by establishing the boundedness of the radiative integral operators and proving the invertibility of the operator matrix associated with the system. A collocation-boundary element method is developed to discretize the differential-integral system. For the non-convex geometries, an element-subdivision algorithm...

Mathematical and numerical studies of non linear ferromagnetic materials

Patrick Joly, Olivier Vacus (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

In this paper we are interested in the numerical modeling of absorbing ferromagnetic materials obeying the non-linear Landau-Lifchitz-Gilbert law with respect to the propagation and scattering of electromagnetic waves. In this work we consider the 1D problem. We first show that the corresponding Cauchy problem has a unique global solution. We then derive a numerical scheme based on an appropriate modification of Yee's scheme, that we show to preserve some important properties of the continuous...

Mathematical modelling and numerical solution of swelling of cartilaginous tissues. Part II: Mixed-hybrid finite element solution

Kamyar Malakpoor, Enrique F. Kaasschieter, Jacques M. Huyghe (2007)

ESAIM: Mathematical Modelling and Numerical Analysis

The swelling and shrinkage of biological tissues are modelled by a four-component mixture theory [J.M. Huyghe and J.D. Janssen, Int. J. Engng. Sci.35 (1997) 793–802; K. Malakpoor, E.F. Kaasschieter and J.M. Huyghe, Mathematical modelling and numerical solution of swelling of cartilaginous tissues. Part I: Modeling of incompressible charged porous media. ESAIM: M2AN41 (2007) 661–678]. This theory results in a coupled system of nonlinear parabolic differential equations together with an algebraic...

Mathematical models for laser-plasma interaction

Rémi Sentis (2005)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

We address here mathematical models related to the Laser-Plasma Interaction. After a simplified introduction to the physical background concerning the modelling of the laser propagation and its interaction with a plasma, we recall some classical results about the geometrical optics in plasmas. Then we deal with the well known paraxial approximation of the solution of the Maxwell equation; we state a coupling model between the plasma hydrodynamics and the laser propagation. Lastly, we consider the...

Mathematical models for laser-plasma interaction

Rémi Sentis (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

We address here mathematical models related to the Laser-Plasma Interaction. After a simplified introduction to the physical background concerning the modelling of the laser propagation and its interaction with a plasma, we recall some classical results about the geometrical optics in plasmas. Then we deal with the well known paraxial approximation of the solution of the Maxwell equation; we state a coupling model between the plasma hydrodynamics and the laser propagation. Lastly, we consider the...

Mathematical study of a petroleum-engineering scheme

Robert Eymard, Raphaèle Herbin, Anthony Michel (2003)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

Models of two phase flows in porous media, used in petroleum engineering, lead to a system of two coupled equations with elliptic and parabolic degenerate terms, and two unknowns, the saturation and the pressure. For the purpose of their approximation, a coupled scheme, consisting in a finite volume method together with a phase-by-phase upstream weighting scheme, is used in the industrial setting. This paper presents a mathematical analysis of this coupled scheme, first showing that it satisfies...

Mathematical study of a petroleum-engineering scheme

Robert Eymard, Raphaèle Herbin, Anthony Michel (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

Models of two phase flows in porous media, used in petroleum engineering, lead to a system of two coupled equations with elliptic and parabolic degenerate terms, and two unknowns, the saturation and the pressure. For the purpose of their approximation, a coupled scheme, consisting in a finite volume method together with a phase-by-phase upstream weighting scheme, is used in the industrial setting. This paper presents a mathematical analysis of this coupled scheme, first showing that it satisfies...

Maximum-norm resolvent estimates for elliptic finite element operators on nonquasiuniform triangulations

Nikolai Yu. Bakaev, Michel Crouzeix, Vidar Thomée (2006)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

In recent years several papers have been devoted to stability and smoothing properties in maximum-norm of finite element discretizations of parabolic problems. Using the theory of analytic semigroups it has been possible to rephrase such properties as bounds for the resolvent of the associated discrete elliptic operator. In all these cases the triangulations of the spatial domain has been assumed to be quasiuniform. In the present paper we show a resolvent estimate, in one and two space dimensions,...

Maximum-norm resolvent estimates for elliptic finite element operators on nonquasiuniform triangulations

Nikolai Yu. Bakaev, Michel Crouzeix, Vidar Thomée (2007)

ESAIM: Mathematical Modelling and Numerical Analysis


In recent years several papers have been devoted to stability and smoothing properties in maximum-norm of finite element discretizations of parabolic problems. Using the theory of analytic semigroups it has been possible to rephrase such properties as bounds for the resolvent of the associated discrete elliptic operator. In all these cases the triangulations of the spatial domain has been assumed to be quasiuniform. In the present paper we show a resolvent estimate, in one and two space dimensions, under...

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